Laboratory Instruments / Protein Analysis Systems Fluidic Analytics
We designed a Serum solution immunoassay platform that allows researchers to characterise and quantify antigen-antibody interactions directly in low or undiluted serum samples.
The ability to quantify both affinity and concentration empowers researchers with a deeper and better understanding of the in vivo
immune response compared to titer alone. In-solution (as opposed to on-surface) characterization allows serum samples to be characterized with minimal dilution. Characterization of protein interactions in solution using. Microfluidic Diffusional Sizing (MDS)
Ability to measure in complex backgrounds such as minimally diluted serum and cell lysate. No binding artifacts or non-specific binding, no surfaceconstraints. Independent determination of antibody concentration and affinity for a comprehensive immune response assessment.
Easy-to-use interface and consumable management. Disposable single use chips and contained waste minimize risk of cross contamination
Understanding how proteins & their interactions effect sickness and health.
Scientists, clinicians & the biopharma industries across the world are trying to understand how proteins & their interactions effect sickness and health. The ability to accurately assess the immune response is crucial to better understand infectious diseases like COVID-19. Traditional immunoassays such as ELISAs offer only an incomplete picture of the immune response against SARS-CoV-2 as they combine affinity & concentration into a single, less-precise measure known as titer. Titers cannot distinguish between large numbers of weak-binding antibodies and small numbers of strong-binding antibodies. Understanding antibody responses on the basis of quantitative fingerprints of affinity & concentration could have major implications for plasma transfer treatments, vaccine and therapeutic development,
and the ongoing monitoring of immunity.
Fluidic Analytics FLUIDITY ONE-W Serum
Disposable single use chips and contained waste minimize risk of cross contamination
Easy-to-use interface and consumable management
Independent determination of antibody concentration and affinity for a comprehensive immune response assessment
No binding artifacts or non-specific binding, no surface-constraints
Ability to measure in complex backgrounds such as minimally diluted serum
Characterization of protein interactions in solution using microfluidic diffusional sizing (MDS)