Molecolar and cell biology / Various Consumables and Kits / Coll 1 Solution Kit
Coll 1 supports cell proliferation on both 2D and 3D levels. Type I collagen is a well-known coating biomaterial used to enhance cell adhesion and proliferation. After seeding on top of our Coll 1 biomaterial, human chondrocytes from the femoral head demonstrated excellent viability, cell proliferation and stretching. However, embedding the living cells into a soft biomaterial such as collagen is a much more challenging task to accomplish. We observed successful proliferation of human dermal fibroblasts embedded into thermally gelated Coll 1 biomaterial. After the initial drop in cell viability related to the 3D printing stress, the cells show great recovery already at day 7 and very good cell viability at day 14. The chondrocytes are homogeneously distributed inside the 3D-printed droplets, forming an extensive interconnected network. As one of the most abundant proteins in the body, Collagen type I is commonly used in tissue engineering and 3D printing applications. Collagen forms fibrous networks that enhances the structural integrity of the extracellular matrix and promotes cell adhesion, growth and tissue morphogenesis. We offer collagen as a concentrated solution, enabling you to customize your biomaterial formulations and create hydrogels, supplemented cell culture coatings and 3D cell culture matrices. For easy neutralization use the Collagen Buffer. Neutralized Coll 1 solutions form stable constructs by thermal crosslinking. Use in combination with FRESH LifeSupport powder for support bath printing. Recommended for use with BIO X, a temperature-controlled printhead and a heated printbed. Not recommended for use with INKREDIBLE+ or INKREDIBLE. Shipping starts from 15th of October.
IKD119261001Coll 1 Solution, 10 mg/ml, 10 ml
KTD119261001Coll 1 Solution Kit, 10 mg/ml, 10 ml
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